Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2764077 | 0.90 | LMNA (0.50) | LMNACYP2C19HIF1A | |
| SCHEMBL2765365 | 0.82 | LMNA (0.41) | LMNA | |
| SCHEMBL11299901 | 0.78 | LMNA (0.58) | LMNAMAP2K1CYP2C19HIF1A | |
| SCHEMBL3430438 | 0.78 | LMNA (0.58) | LMNAMAP2K1CYP2C19HIF1A | |
| SCHEMBL15760478 | 0.77 | LMNA (0.67) | LMNAMAP2K1CYP2C19HIF1A | |
| SCHEMBL8978151 | 0.77 | LMNA (0.71) | LMNAMAP2K1CYP2C19HIF1A | |
| SCHEMBL1744046 | 0.77 | LMNA (0.53) | LMNAMAP2K1CYP2C19HIF1A | |
| SCHEMBL9853840 | 0.76 | LMNA (0.74) | LMNAMAP2K1 | |
| SCHEMBL17264622 | 0.76 | LMNA (0.83) | LMNAMAP2K1CYP2C19HIF1A | |
| SCHEMBL2763618 | 0.76 | LMNA (0.56) | LMNAMAP2K1CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855997-A4 | FORMYL DERIVATIVES AS NONIONIC CONTRAST MEDIA | BIOPHYSICA INC (US) | 1998-10-07 | — | — | EP | disclosed |
| EP-0855997-A1 | FORMYL DERIVATIVES AS NONIONIC CONTRAST MEDIA | BIOPHYSICA, INC. (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997000240-A1 | FORMYL DERIVATIVES AS NONIONIC CONTRAST MEDIA | BIOPHYSICA FOUNDATION (US) | 1997-01-03 | — | — | WO | disclosed |