Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31614294 | 1.00 | MT-CO2 (0.55) | MT-CO2FOLH1PTGS1PTGS2MET | |
| SCHEMBL8459762 | 0.87 | FOLH1 (0.44) | MT-CO2FOLH1PTGS1PTGS2MET | |
| SCHEMBL13176797 | 0.84 | MT-CO2 (0.59) | MT-CO2PTGS1PTGS2MEN1GAA | |
| SCHEMBL8459765 | 0.83 | FOLH1 (0.50) | MT-CO2FOLH1METMEN1GAA | |
| SCHEMBL27823628 | 0.82 | MET (0.47) | FOLH1METMEN1GAAKMT2A | |
| SCHEMBL2742620 | 0.82 | ALDH1A1 (0.51) | MT-CO2PTGS1PTGS2MEN1GAA | |
| SCHEMBL1202580 | 0.81 | AKR1C3 (0.47) | FOLH1PTGS1PTGS2METMEN1 | |
| SCHEMBL7050577 | 0.81 | FOLH1 (0.50) | MT-CO2FOLH1PTGS1PTGS2KMT2A | |
| SCHEMBL11216724 | 0.80 | ALDH1A1 (0.58) | MT-CO2PTGS1PTGS2MEN1GAA | |
| SCHEMBL490875 | 0.80 | TSHR (0.59) | MT-CO2FOLH1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1735408-A | Receptor function controlling agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-15 | — | — | CN | disclosed |