Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 10/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | RGS12 | O14924 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080284 | 1.00 | PLA2G2A (0.65) | PLA2G2ALMNACYP1A2CYP3A4CYP2C9 | |
| Glucametacin SCHEMBL27641193 | 0.86 | PTGS2 (0.72) | PTGS2 | |
| Glucametacin SCHEMBL24511 | 0.86 | PTGS2 (0.72) | PTGS2 | |
| Glucametacin SCHEMBL5081097 | 0.86 | PTGS2 (0.72) | PTGS2 | |
| Glucametacin SCHEMBL30344903 | 0.86 | PTGS2 (0.72) | PTGS2 | |
| Glucametacin SCHEMBL9988209 | 0.81 | PTGS2 (0.63) | PTGS2 | |
| SCHEMBL8300729 | 0.80 | PLA2G2A (1.00) | PLA2G2ALMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1322507 | 0.77 | LMNA (1.00) | PLA2G2ALMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8296281 | 0.76 | PLA2G2A (0.90) | PLA2G2ALMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8292280 | 0.75 | LMNA (0.78) | PLA2G2ALMNACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242146-B2 | Administering ROFLUMILAS and DICLOFENAC; antiinflammatory agents | NYCOMED GMBH (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20080255209-A1 | Combination of a NSAID and a PDE-4 inhibitor | NYCOMED GMBH (DE) | 2008-10-16 | — | — | US | disclosed |