Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | IAPP | P10997 | 2/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17789590 | 0.81 | GCGR (0.38) | PRKCIHSP90AB1CNR1CNR2TSHR | |
| SCHEMBL27641337 | 0.79 | HSP90AB1 (0.35) | PRKCIHSP90AB1LDHALDHBCNR1 | |
| SCHEMBL30027246 | 0.75 | CNR1 (0.50) | PRKCICNR1CNR2KDM4EALDH1A1 | |
| SCHEMBL1760417 | 0.75 | CNR1 (0.50) | PRKCICNR1CNR2KDM4EALDH1A1 | |
| SCHEMBL9821864 | 0.75 | PRKCI (0.44) | PRKCIHSP90AB1MCL1KDM4EFFAR1 | |
| SCHEMBL11439654 | 0.73 | LMNA (0.42) | PRKCIHSP90AB1KDM4EALDH1A1HPGD | |
| SCHEMBL27800576 | 0.73 | MEN1 (0.36) | HSP90AB1HSP90AA1KDM4EALDH1A1HPGD | |
| SCHEMBL27691525 | 0.72 | PTGS1 (0.33) | HSP90AB1HSP90AA1KDM4EHPGDFFAR1 | |
| SCHEMBL27691694 | 0.72 | ADRB2 (0.39) | HSP90AB1HSP90AA1KDM4EFFAR1 | |
| SCHEMBL27831460 | 0.72 | PTGS1 (0.33) | HSP90AB1HSP90AA1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882524-A | 4- ((phenoxyalkyl) thio) -phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA NV (BE) | 2006-12-20 | — | — | CN | disclosed |