Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | DBH | P09172 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689599 | 0.81 | ADRB2 (0.35) | MEN1KMT2AMAPTLMNASLC6A2 | |
| SCHEMBL28765674 | 0.81 | GRM1 (0.37) | GRM1CYP3A4TSHR | |
| SCHEMBL11038353 | 0.79 | GABRA1 (0.52) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL27686304 | 0.78 | MAPK1 (0.35) | MEN1KMT2AMAPTLMNASLC6A2 | |
| SCHEMBL27831460 | 0.78 | PTGS1 (0.33) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL27691694 | 0.78 | ADRB2 (0.39) | ADRA1AKDM4EPTGS1HSP90AA1HSP90AB1 | |
| SCHEMBL27691525 | 0.78 | PTGS1 (0.33) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL28818939 | 0.78 | TRPA1 (0.46) | MEN1KMT2AMAPTLMNASLC6A2 | |
| SCHEMBL27705286 | 0.75 | TDP1 (0.43) | MEN1KMT2AMAPTSLC6A2ADRA1A | |
| SCHEMBL27711675 | 0.74 | HSP90AA1 (0.33) | MEN1KMT2AKDM4EPTGS1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101955470-A | Glutamate receptor potentiators | LILLY CO ELI | 2011-01-26 | — | — | CN | disclosed |