Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27662343 | 0.80 | TSHR (0.42) | ALDH1A1POLBMEN1KMT2ACES2 | |
| SCHEMBL9835405 | 0.80 | CES2 (0.41) | LMNAKDM4EALDH1A1POLBTDP1 | |
| SCHEMBL27662346 | 0.78 | CYP1A2 (0.39) | LMNAKDM4EALDH1A1CES2CES1 | |
| SCHEMBL27616188 | 0.78 | CYP3A4 (0.44) | LMNAKDM4EALDH1A1TDP1ALOX15 | |
| SCHEMBL1635424 | 0.77 | NPSR1 (0.46) | ALDH1A1POLBNPSR1MEN1KMT2A | |
| SCHEMBL28763259 | 0.77 | MT-CO2 (0.57) | LMNAKDM4EALDH1A1POLBTDP1 | |
| SCHEMBL10780259 | 0.77 | LMNA (0.47) | LMNAKDM4EALDH1A1POLBTDP1 | |
| SCHEMBL28760865 | 0.76 | HTR3E (0.46) | LMNAALDH1A1FSCN1MEN1KMT2A | |
| SCHEMBL17671229 | 0.76 | ALOX15 (0.50) | LMNAKDM4EALDH1A1POLBTDP1 | |
| SCHEMBL3150016 | 0.76 | LMNA (0.46) | LMNAKDM4EALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101270097-B | Process for production of 1-aryl-5-(trifluoromethyl)-1H-tetrazoles | TOYO BOSEKI | 2011-04-13 | — | — | CN | disclosed |
| CN-100424069-C | Preparation method of N-aryl-2, 2, 2-trifluoro acetimidoyl chloride | TOYO KASEI KOGYO CO LTD (JP) | 2008-10-08 | — | — | CN | disclosed |
| CN-101270097-A | Process for production of 1-aryl-5-(trifluoromethyl)-1H-tetrazoles | TOYO KASEI KOGYO CO LTD (JP) | 2008-09-24 | — | — | CN | disclosed |
| CN-1863765-A | Preparation method of 1-aryl-5- (trifluoromethyl) -1H-tetrazole | TOYO KASEI KOGYO CO LTD (JP) | 2006-11-15 | — | — | CN | disclosed |