Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27623186 | 0.83 | MAPK1 (0.56) | LMNAMAPTNPSR1HTTGAA | |
| SCHEMBL27857403 | 0.82 | HTR1A (0.50) | LMNAMAPTHTTTSHRMAPK1 | |
| SCHEMBL27623187 | 0.81 | LMNA (0.46) | LMNAMAPTNPSR1HTTGAA | |
| SCHEMBL28322328 | 0.80 | AKR1C3 (0.54) | LMNAMAPTTSHRMAPK1ITGB3 | |
| SCHEMBL24677569 | 0.78 | MEN1 (0.51) | LMNAMAPTNPSR1TSHRHTR1A | |
| SCHEMBL27662780 | 0.77 | AGXT (0.56) | LMNAMAPTITGB3ITGA2BALDH1A1 | |
| SCHEMBL27468903 | 0.75 | AGXT (0.49) | LMNAITGB3ITGA2BHTR1AHTR7 | |
| SCHEMBL10282747 | 0.73 | MEN1 (0.53) | LMNAMAPTNPSR1HTTTSHR | |
| SCHEMBL13063408 | 0.73 | AGXT (0.46) | LMNAMAPTNPSR1HTTTSHR | |
| SCHEMBL689414 | 0.72 | GPR119 (0.56) | LMNAMAPTNPSR1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1747732-A | 2-aminocarbonyl-quinoline compounds as platelet adenosine diphosphate receptor antagonists | SCHERING AG (DE) | 2006-03-15 | — | — | CN | claimed |
| CN-1747732-A | 2-aminocarbonyl-quinoline compounds as platelet adenosine diphosphate receptor antagonists | SCHERING AG (DE) | 2006-03-15 | — | — | CN | disclosed |