Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013395 | 0.75 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL5013401 | 0.72 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL24283332 | 0.68 | MEN1 (0.50) | MEN1KMT2AALDH1A1KDM4EDRD4 | |
| SCHEMBL6030916 | 0.66 | MAPT (0.83) | MEN1KMT2AALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL10923734 | 0.65 | SIGMAR1 (0.60) | MEN1KMT2AALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL7937990 | 0.65 | ALDH1A1 (0.95) | ALDH1A1KDM4ESIGMAR1LSSSMN1; SMN2 | |
| SCHEMBL23851111 | 0.65 | ALDH1A1 (0.87) | MEN1KMT2AALDH1A1KDM4ESIGMAR1 | |
| Hydrochloric Acid SCHEMBL6030550 | 0.64 | MAPT (0.81) | MEN1KMT2AALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL27666181 | 0.63 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTDRD4DRD2 | |
| SCHEMBL2095961 | 0.63 | MEN1 (0.55) | MEN1KMT2AALDH1A1KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |