Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.50 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666764 | 0.82 | L3MBTL1 (0.53) | PLOD2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL19282739 | 0.82 | NPC1 (0.51) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL6921708 | 0.81 | LMNA (0.55) | PLOD2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL16931655 | 0.79 | KMT2A (0.70) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL13005928 | 0.77 | LMNA (0.54) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL659602 | 0.76 | ALDH1A1 (0.61) | PLOD2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL31268672 | 0.76 | HDAC1 (0.62) | ALDH1A1LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL2732281 | 0.76 | HDAC1 (0.62) | ALDH1A1LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL14736574 | 0.75 | CYP3A4 (0.51) | PLOD2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28294170 | 0.75 | RXFP1 (0.53) | ALDH1A1LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755484-B | BACE inhibitor | ELI LILLY AND CO. (US) | 2016-02-17 | — | — | CN | disclosed |
| CN-104755484-A | Bace inhibitors | LILLY CO ELI | 2015-07-01 | — | — | CN | disclosed |
| CN-101119994-A | Nicotinic acetycholine receptor ligands | ASTRAZENECA AB (SE) | 2008-02-06 | — | — | CN | disclosed |
| CN-1918166-A | Nicotinic acetylcholine receptor ligands | ASTRAZENECA AB (SE) | 2007-02-21 | — | — | CN | disclosed |