Sugi Predict

Sugi Predict / Compounds / SCHEMBL2764994

SCHEMBL2764994

SCHEMBL2764994

CCOC(=O)[C@@H](N)C(C)O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.44
▸ ALDH1A1 P00352 3/20 0.42
▸ METAP2 P50579 8/20 0.40
▸ METAP1 P53582 6/20 0.40
▸ LMNA P02545 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ MGAM O43451 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ SI P14410 1/20 0.39
▸ MGAM2 Q2M2H8 1/20 0.39
▸ SOAT1 P35610 1/20 0.39
▸ CYP2D6 P10635 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ HPGD P15428 1/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ CAD P27708 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1671835 1.00 ALOX15 (0.44) ALOX15ALDH1A1METAP2METAP1LMNA
SCHEMBL1338583 1.00 ALOX15 (0.44) ALOX15ALDH1A1METAP2METAP1LMNA
Hydrochloric Acid SCHEMBL2407084 0.98 ALOX15 (0.42) ALOX15ALDH1A1METAP2METAP1LMNA
Hydrochloric Acid SCHEMBL21250188 0.98 ALOX15 (0.42) ALOX15ALDH1A1METAP2METAP1LMNA
Hydrochloric Acid SCHEMBL2407086 0.98 ALOX15 (0.42) ALOX15ALDH1A1METAP2METAP1LMNA
SCHEMBL196141 0.83 ALOX15 (0.46) ALOX15ALDH1A1METAP2METAP1LMNA
SCHEMBL6389387 0.83 ALOX15 (0.46) ALOX15ALDH1A1METAP2METAP1LMNA
SCHEMBL6036176 0.83 ALOX15 (0.46) ALOX15ALDH1A1METAP2METAP1LMNA
SCHEMBL135322 0.83 ALOX15 (0.46) ALOX15ALDH1A1METAP2METAP1LMNA
Hydrochloric Acid SCHEMBL8848952 0.82 ALOX15 (0.50) ALOX15ALDH1A1METAP2METAP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117126897-A Method for preparing (2S, 3R) -p-methylsulfonyl phenylserine ethyl ester 弈柯莱生物科技(集团)股份有限公司 2023-11-28 — — CN claimed
CN-120718973-A One-step enzymatic synthesis technology of (2S, 3R) -p-methylsulfonyl phenylserine ethyl ester 台州凌峰生物科技有限公司 2025-09-30 — — CN disclosed
US-20250074887-A1 PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF Sea Pharmaceuticals LLC. (US) 2025-03-06 — — US disclosed
US-20240336601-A1 4-PHENYL-INDOLE DERIVATIVES AND RELATED USES CHULALONG UNIVERSITY (TH) 2024-10-10 — — US disclosed
CN-117126897-A Method for preparing (2S, 3R) -p-methylsulfonyl phenylserine ethyl ester 弈柯莱生物科技(集团)股份有限公司 2023-11-28 — — CN disclosed
WO-2022147302-A1 4-PHENYL-INDOLE DERIVATIVES AND RELATED USES CHULALONGKORN UNIVERSITY (TH) 2022-07-07 — — WO disclosed
US-9617256-B2 Antibacterial agents ACHAOGEN, INC. (US) 2017-04-11 — — US disclosed
US-20170088549-A1 ANTIBACTERIAL AGENTS ACHAOGEN, INC. 2017-03-30 — — US disclosed
CN-106117300-A A kind of new compound for treating carcinoma of prostate 郭明山 2016-11-16 — — CN disclosed
EP-2170814-B1 ANTIBACTERIAL AGENTS ACHAOGEN INC (US) 2016-08-17 — — EP disclosed
EP-0956033-A1 TOTAL SYNTHESIS OF THE AMINO HIP ANALOGUE OF DIDEMNIN A THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1999-11-17 — — EP disclosed
WO-1998017302-A9 TOTAL SYNTHESIS OF THE AMINO HIP ANALOGUE OF DIDEMNIN A — 1998-10-15 — — WO disclosed
WO-1998017302-A1 TOTAL SYNTHESIS OF THE AMINO HIP ANALOGUE OF DIDEMNIN A THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1998-04-30 — — WO disclosed
EP-0216832-B1 NOVEL INSULIN DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE DERIVATIVES NOVO NORDISK A/S (DK) 1990-08-29 — — EP disclosed
EP-0216832-A1 NOVEL INSULIN DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE DERIVATIVES. NORDISK GENTOFTE (DK) 1987-04-08 — — EP disclosed
WO-1986005496-A1 NOVEL INSULIN DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE DERIVATIVES NORDISK GENTOFTE A/S (DK) 1986-09-25 — — WO disclosed
EP-0088117-B1 PROCESS FOR PREPARING HUMAN INSULIN OR B-30 ESTERS THEREOF NORDISK INSULINLABORATORIUM (DK) 1986-09-24 — — EP disclosed
US-4601979-A Process for preparing human insulin or B-30 esters thereof NORDISK INSULINLABORATORIUM (DK) 1986-07-22 — — US disclosed
EP-0088117-A1 PROCESS FOR PREPARING HUMAN INSULIN OR B-30 ESTERS THEREOF. NORDISK INSULINLAB (DK) 1983-09-14 — — EP disclosed
WO-1983001074-A1 ENZYMATIC PREPARATION OF HUMAN INSULIN OR B-30 ESTERS THEREOF ANDRESEN, FINN, HEDE 1983-03-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074887-A1 PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF GABRQ, GRIK5, CYP3A7 ALOX15 616/4885ALDH1A1 501/4885METAP2 2588/4885
US-20170088549-A1 ANTIBACTERIAL AGENTS MRPL21, SI, ABCB11 ALOX15 1387/4885ALDH1A1 687/4885METAP2 2394/4885
US-20240336601-A1 4-PHENYL-INDOLE DERIVATIVES AND RELATED USES PDCD1, PDCD1LG2, CD274 ALOX15 1373/4885ALDH1A1 56/4885METAP2 3256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.