Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | PNMT | P11086 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16814941 | 0.83 | DPP4 (0.52) | GABRA1GABRB2PNMTGABRG2GABRB3 | |
| SCHEMBL23771351 | 0.82 | GABRA1 (0.43) | GABRA1GABRB2PNMTGABRG2GABRB3 | |
| SCHEMBL3842659 | 0.82 | TAAR1 (0.54) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL2778070 | 0.82 | PNMT (0.41) | GABRA1GABRB2PNMTGABRG2GABRB3 | |
| SCHEMBL394464 | 0.80 | TSHR (0.55) | GABRA1GABRB2PNMTDPP4TSHR | |
| SCHEMBL10349024 | 0.80 | GABRA1 (0.42) | GABRA1GABRB2PNMTGABRG2GABRB3 | |
| SCHEMBL19553673 | 0.80 | PNMT (0.54) | GABRA1GABRB2PNMTGABRG2GABRB3 | |
| SCHEMBL13976077 | 0.80 | GABRA1 (0.42) | GABRA1GABRB2PNMTGABRG2GABRB3 | |
| SCHEMBL9839884 | 0.80 | GABRA1 (0.48) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL23005062 | 0.80 | NISCH (0.41) | LMNACYP1A2CYP3A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896125-B1 | A RUBBER COMPOSITION AND A RUBBER PRODUCT | GOODYEAR TIRE & RUBBER (US) | 2024-10-02 | — | — | EP | claimed |
| EP-2678364-B1 | RHEOLOGICAL AGENT FOR RADIATION-CURABLE COATING MATERIALS | BASF SE (DE) | 2015-04-08 | — | — | EP | claimed |
| WO-2012113739-A1 | RHEOLOGICAL AGENT FOR RADIATION-CURABLE COATING MATERIALS | BASF SE (DE) | 2012-08-30 | — | — | WO | claimed |
| EP-2178828-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | Sika Technology AG (CH) | 2010-04-28 | — | — | EP | claimed |
| WO-2009010522-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | SIKA TECHNOLOGY AG (CH) | 2009-01-22 | — | — | WO | claimed |
| EP-2017260-A1 | Aldimines and compounds containing aldimine | Sika Technology AG (CH) | 2009-01-21 | — | — | EP | claimed |
| WO-2007006585-A2 | SYNTHESIS OF A POROUS AND/OR STRATIFIED STRUCTURE MANGANESE OXIDE | ELSPER RUEDIGER (DE) | 2007-01-18 | — | — | WO | claimed |
| EP-0627912-B1 | GELS FOR ENCAPSULATION OF BIOLOGICAL MATERIALS | UNIV TEXAS (US) | 2004-05-12 | — | — | EP | claimed |
| US-11858946-B2 | Small molecules active against gram-negative bacteria | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-01-02 | — | — | US | disclosed |
| US-11858946-B2 | Small molecules active against gram-negative bacteria | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230381149-A1 | RILUZOLE PRODRUGS AND THEIR USE | BEETLEJUICE SA LLC, AS PURCHASER AGENT | 2023-11-30 | — | — | US | disclosed |
| US-20230365588-A1 | DIOL DESYMMETRIZATION BY NUCLEOPHILIC AROMATIC SUBSTITUTION | AMGEN INC. (US) | 2023-11-16 | — | — | US | disclosed |
| EP-3661921-B1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NODTHERA LTD (GB) | 2023-10-18 | — | — | EP | disclosed |
| US-11697804-B2 | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-07-11 | — | — | US | disclosed |
| EP-1219612-A1 | 2-IMINO-1,3-THIAZINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-20010020075-A1 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-09-06 | — | — | US | disclosed |
| EP-1113026-A2 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-04 | — | — | EP | disclosed |
| EP-0279239-B1 | MICROBICIDES | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| EP-0279239-A1 | Microbicides | CIBA-GEIGY AG (CH) | 1988-08-24 | — | — | EP | disclosed |
| EP-0198369-A2 | Process for the preparation of perylene-3,4,9,10-tetracarboxylic-acid aryl imides | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365588-A1 | DIOL DESYMMETRIZATION BY NUCLEOPHILIC AROMATIC SUBSTITUTION | MCL1, BAK1, BCL2A1 | GABRA1 3917/4885GABRB2 4436/4885PNMT 2008/4885 |
| US-11697804-B2 | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy | POLRMT, HDGF, PCNP | GABRA1 4624/4885GABRB2 4556/4885PNMT 1117/4885 |
| US-11858946-B2 | Small molecules active against gram-negative bacteria | PGLS, MRPL21, CLPP | GABRA1 3819/4885GABRB2 2394/4885PNMT 1477/4885 |
| US-20230381149-A1 | RILUZOLE PRODRUGS AND THEIR USE | APEH, ALDH1A2, UGT1A9 | GABRA1 1837/4885GABRB2 1810/4885PNMT 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.