Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227815 | 0.87 | PTGS2 (0.42) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL5229334 | 0.83 | MEN1 (0.46) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL27502850 | 0.79 | MEN1 (0.53) | MEN1KMT2AMAPTTP53HPGD | |
| SCHEMBL3119255 | 0.79 | MEN1 (0.40) | MEN1KMT2AMAPTTP53HPGD | |
| SCHEMBL16166567 | 0.79 | MEN1 (0.40) | MEN1KMT2AMAPTTP53HPGD | |
| SCHEMBL31042467 | 0.79 | MEN1 (0.40) | MEN1KMT2AMAPTTP53HPGD | |
| SCHEMBL31498780 | 0.78 | GABRA1 (0.46) | MEN1KMT2AMAPTTP53HPGD | |
| SCHEMBL14268018 | 0.78 | GABRA1 (0.46) | MEN1KMT2AMAPTTP53HPGD | |
| SCHEMBL27634469 | 0.78 | CES2 (0.38) | — | |
| SCHEMBL27671813 | 0.77 | LMNA (0.57) | MEN1KMT2AMAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1829709-A | Bicyclic imidazol derivatives against flaviviridae | GENELABS TECH INC (US) | 2006-09-06 | — | — | CN | disclosed |