Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675479 | 0.92 | PDE11A (0.41) | ACHE | |
| SCHEMBL27675572 | 0.90 | ACHE (0.47) | ACHEAPPKMT2ATNFNOD1 | |
| SCHEMBL27655444 | 0.89 | ACHE (0.47) | ACHEAPPKMT2ATNFNOD1 | |
| SCHEMBL27655552 | 0.88 | ACHE (0.45) | ACHEAPPKMT2ATNFNOD1 | |
| SCHEMBL27675500 | 0.87 | ACHE (0.45) | ACHEAPPKMT2ATNFNOD1 | |
| SCHEMBL27655434 | 0.85 | KDM4E (0.42) | — | |
| SCHEMBL27675451 | 0.85 | GAA (0.43) | ACHEAPPKMT2ATNFNOD1 | |
| SCHEMBL27675511 | 0.84 | PDE5A (0.41) | ACHE | |
| SCHEMBL27655435 | 0.83 | ACHE (0.42) | ACHEAPPKMT2ATNFNOD1 | |
| SCHEMBL27655448 | 0.83 | ESR1 (0.43) | ACHEAPPKMT2ATNFNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1875023-A | Use of thienopyrimidines | MERCK PATENT GMBH (DE) | 2006-12-06 | — | — | CN | disclosed |