SCHEMBL2765671

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2765675	1.00	ADAMTS5 (0.69)	ADAMTS5MAPK1CYP2C19CA12CA1
	SCHEMBL5494344	1.00	ADAMTS5 (0.69)	ADAMTS5MAPK1CYP2C19CA12CA1
	SCHEMBL2764179	0.86	ADAMTS5 (0.86)	ADAMTS5MAPK1CYP2C19MMP2ADAM17
	SCHEMBL2764182	0.86	ADAMTS5 (0.86)	ADAMTS5MAPK1CYP2C19MMP2ADAM17
	SCHEMBL5495201	0.83	ADAMTS5 (0.64)	ADAMTS5MAPK1CYP2C19GHSRADAM17
	SCHEMBL2763654	0.83	ADAMTS5 (0.64)	ADAMTS5MAPK1CYP2C19GHSRADAM17
	SCHEMBL2763655	0.83	ADAMTS5 (0.64)	ADAMTS5MAPK1CYP2C19GHSRADAM17
	SCHEMBL2766202	0.83	ADAMTS5 (0.66)	ADAMTS5MAPK1CYP2C19ADAM17MAPT
	SCHEMBL2766204	0.83	ADAMTS5 (0.66)	ADAMTS5MAPK1CYP2C19ADAM17MAPT
	SCHEMBL2766668	0.82	ADAMTS5 (0.72)	ADAMTS5MAPK1CYP2C19KAT6AADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.