Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27466535 | 0.85 | MAPT (0.42) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27327851 | 0.84 | LMNA (0.47) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28031644 | 0.84 | L3MBTL1 (0.48) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28985286 | 0.80 | PKM (0.49) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27610500 | 0.78 | ALDH1A1 (0.43) | LMNAKMT2AALDH1A1TSHRMAPT | |
| SCHEMBL18801901 | 0.78 | LMNA (0.51) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL27584050 | 0.78 | EGFR (0.43) | LMNAKMT2AALDH1A1TSHRMAPT | |
| SCHEMBL3393735 | 0.77 | GPR35 (0.46) | MEN1KMT2AALDH1A1TSHRCTSD | |
| SCHEMBL7166893 | 0.77 | TDP1 (0.46) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7913797 | 0.77 | PDGFRB (0.48) | LMNAMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100558701-C | N-(2-phenylethyl) sulfone amide derivative as integrin alpha 4 antagonists | ALMIRALL PRODESFARMA SA (ES) | 2009-11-11 | — | — | CN | disclosed |
| CN-1816523-A | N-(2-phenylethyl)sulfamide derivatives as integrin alpha4 antagonists | ALMIRALL PRODESFARMA SA (ES) | 2006-08-09 | — | — | CN | disclosed |