Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.61 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.61 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31656115 | 0.74 | TRIM24 (0.56) | CSNK2A2CSNK2BCSNK2A1CNR2MAPT | |
| SCHEMBL27648661 | 0.73 | BRPF1 (0.39) | CSNK2A2CSNK2BCSNK2A1NR4A2BRPF1 | |
| SCHEMBL27680777 | 0.72 | GPR35 (0.37) | CSNK2A2CSNK2BCSNK2A1MAPTALDH1A1 | |
| SCHEMBL28100554 | 0.69 | GPR84 (0.51) | BRPF1 | |
| SCHEMBL27984527 | 0.69 | NR4A2 (0.63) | NR4A2MAPTALDH1A1LMNAPRKAB2 | |
| SCHEMBL28770407 | 0.69 | NR4A2 (0.61) | NR4A2MAPTALDH1A1 | |
| SCHEMBL28170258 | 0.68 | PRKAB2 (0.48) | NR4A2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL27447876 | 0.68 | BRPF1 (0.42) | CSNK2A2CSNK2BCSNK2A1CNR2NR4A2 | |
| SCHEMBL27036397 | 0.67 | CSNK2A2 (0.50) | CSNK2A2CSNK2BCSNK2A1CNR2MAPT | |
| SCHEMBL17665238 | 0.67 | MAPT (0.49) | CSNK2A2CSNK2BCSNK2A1CNR2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1953747-A | Diphenyl-indol-2-on compounds and their use in the treatment of cancer | TOPOTARGET AS (DK) | 2007-04-25 | — | — | CN | disclosed |