SCHEMBL27664489

SCHEMBL27664489

C=CCCC(C(=O)OC(C)(C)C)C(N)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.34
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34
USP2 O75604 2/20 0.33
CYP3A4 P08684 2/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
LMNA P02545 1/20 0.31
RECQL P46063 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
TSHR P16473 2/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28761291 0.89 MAPT (0.43) NOS1NOS3NOS2USP2CYP3A4
SCHEMBL27664476 0.83 CYP3A4 (0.33) NOS1NOS3NOS2CYP3A4SMN1; SMN2
SCHEMBL10166818 0.81 LTA4H (0.36) NOS1NOS3NOS2USP2CYP3A4
SCHEMBL29831595 0.80 NOS1 (0.37) NOS1NOS3NOS2MEN1KMT2A
SCHEMBL27537985 0.78 SMN1; SMN2 (0.36) NOS1NOS3NOS2USP2CYP3A4
SCHEMBL11066540 0.78 LMNA (0.35) NOS1NOS3NOS2USP2CYP3A4
SCHEMBL9644339 0.77 GABRP (0.42) NOS1NOS3NOS2MAPTLMNA
SCHEMBL29059466 0.76 TSHR (0.37) NOS1NOS3NOS2USP2CYP3A4
SCHEMBL7387563 0.75 NOS1 (0.36) NOS1NOS3NOS2ALDH1A1LMNA
SCHEMBL3034322 0.75 NOS1 (0.36) NOS1NOS3NOS2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1986520-A Preparing process of optically active long chain N-Boc-amino acid with end olefinic bond YAOMINGKANGDE NEW MEDICINE DEV (CN) 2007-06-27 CN disclosed