Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27411781 | 0.81 | ALDH1A1 (0.39) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL11066540 | 0.81 | LMNA (0.35) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL29059466 | 0.80 | TSHR (0.37) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL27408320 | 0.80 | CYP2D6 (0.37) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL5026580 | 0.80 | CYP2D6 (0.37) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL10965572 | 0.79 | MEN1 (0.37) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL10166818 | 0.79 | LTA4H (0.36) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL27664489 | 0.78 | NOS1 (0.34) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL27604138 | 0.78 | TDP1 (0.38) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 | |
| SCHEMBL2332499 | 0.76 | LMNA (0.39) | SMN1; SMN2USP2CYP3A4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153110-A | Synthetic method of atorvastatin calcium chiral intermediate | UNIV HENAN NORMAL | 2015-12-16 | — | — | CN | claimed |
| CN-101098859-A | Pyrimidone compounds and preparation and application thereof | ZHEJIANG HISUN PHARMACEUTICAL (CN) | 2008-01-02 | — | — | CN | claimed |
| CN-103936680-B | The preparation method of rosuvastain calcium known impurities | 润泽制药(苏州)有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-104230817-A | Preparation method of 3, 5-dihydroxy-6-heptenoic acid derivatives | NANJING MDC MEDICINE SCIENCE & TECHNOLOGY CO LTD | 2014-12-24 | — | — | CN | disclosed |
| CN-102079726-B | Miazine compounds, intermediates of miazine compounds, preparation method of intermediates and miazine compounds as well as application of miazine compound | SHANGHAI INST PHARM INDUSTRY | 2013-04-03 | — | — | CN | disclosed |
| CN-101967123-B | 2-cyclopropyl-4-(N-methyl substituted anilino) quinoline compound as well as intermediate, preparation method and application thereof | SHANGHAI INST PHARM INDUSTRY | 2012-06-27 | — | — | CN | disclosed |
| CN-102079726-A | Miazine compounds, intermediates of miazine compounds, preparation method of intermediates and miazine compounds as well as application of miazine compound | SHANGHAI INST PHARM INDUSTRY | 2011-06-01 | — | — | CN | disclosed |
| CN-101967123-A | 2-cyclopropyl-4-(N-methyl substituted anilino) quinoline compound as well as intermediate, preparation method and application thereof | SHANGHAI INST PHARM INDUSTRY | 2011-02-09 | — | — | CN | disclosed |
| CN-101098859-A | Pyrimidone compounds and preparation and application thereof | ZHEJIANG HISUN PHARMACEUTICAL (CN) | 2008-01-02 | — | — | CN | disclosed |
| CN-1088204-A | 6-heptynoic acid and heptenoic acid compound | SAGAMI CHEMICAL RESERCH CENTER (JP) | 1994-06-22 | — | — | CN | disclosed |