SCHEMBL2766479

SCHEMBL2766479

C=CC(=O)OC(C)COC(=O)C1CCC=CC1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1613930 0.92 TSHR (0.37) TSHR
SCHEMBL3735549 0.84 TSHR (0.36) TSHR
SCHEMBL9811787 0.80 TSHR (0.40) TSHR
SCHEMBL11340916 0.78 MAPT (0.30)
SCHEMBL1151516 0.78 TSHR (0.41) TSHR
SCHEMBL691186 0.77 TSHR (0.46) TSHR
SCHEMBL5084661 0.77 MAPT (0.36) TSHR
SCHEMBL10520704 0.76 POLB (0.38) TSHR
SCHEMBL11619198 0.75
SCHEMBL2200972 0.75 TSHR (0.37) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6177524-B1 RING-OPENING ADDITION PRODUCT OF (METH)ACRYLOYL GROUP-CONTAINING CARBOXYLIC ACID TO EPOXY GROUPS OF AN EPOXIDED CONJUGATED DIENE-VINYLAROMATIC BLOCK POLYMER DAICEL CHEMICAL INDUSTRIES LTD. (JP) 2001-01-23 US claimed
EP-0899275-A1 BLOCK COPOLYMER HAVING (METH)ACRYLOYL GROUPS IN THE SIDE CHAINS AND COMPOSITION CONTAINING THE SAME DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 1999-03-03 EP claimed
EP-3018118-B1 BASE GENERATOR, BASE-REACTIVE COMPOSITION CONTAINING SAID BASE GENERATOR, AND BASE GENERATION METHOD FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2023-07-05 EP disclosed
EP-3327002-B1 ACID-RESISTANT BASE AND/OR RADICAL GENERATOR, AND CURABLE RESIN COMPOSITION CONTAINING SAID BASE AND/OR RADICAL GENERATOR FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2020-08-19 EP disclosed
US-10428015-B2 Acid-resistant base and/or radical generator, and curable resin composition containing said base and/or radical generator FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-01 US disclosed
US-10428014-B2 Base generator, base-reactive composition containing said base generator, and base generation method FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-01 US disclosed
US-20190002403-A1 ACID-RESISTANT BASE AND/OR RADICAL GENERATOR, AND CURABLE RESIN COMPOSITION CONTAINING SAID BASE AND/OR RADICAL GENERATOR FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-01-03 US disclosed
EP-3098226-B1 BORATE-BASED BASE GENERATOR, AND BASE-REACTIVE COMPOSITION COMPRISING SUCH BASE GENERATOR FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2018-12-12 EP disclosed
US-10100070-B2 Borate-based base generator, and base-reactive composition comprising such base generator FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2018-10-16 US disclosed
EP-3327002-A1 ACID-RESISTANT BASE AND/OR RADICAL GENERATOR, AND CURABLE RESIN COMPOSITION CONTAINING SAID BASE AND/OR RADICAL GENERATOR Wako Pure Chemical Industries, Ltd. (JP) 2018-05-30 EP disclosed
EP-3098226-A1 BORATE-BASED BASE GENERATOR, AND BASE-REACTIVE COMPOSITION COMPRISING SUCH BASE GENERATOR Wako Pure Chemical Industries, Ltd. (JP) 2016-11-30 EP disclosed
US-20070166636-A1 Electrophotographic toner and electrophotographic developer and image forming method FUJI XEROX CO., LTD. (JP) 2007-07-19 US disclosed
US-20060071203-A1 Coating composition and optical article TOKUYAMA CORPORATION (JP) 2006-04-06 US disclosed
EP-1568739-A1 COATING COMPOSITION AND OPTICAL ARTICLE Tokuyama Corporation (JP) 2005-08-31 EP disclosed
EP-0785034-B1 Coating method KANSAI PAINT CO LTD (JP) 2002-11-06 EP disclosed
US-6177524-B1 RING-OPENING ADDITION PRODUCT OF (METH)ACRYLOYL GROUP-CONTAINING CARBOXYLIC ACID TO EPOXY GROUPS OF AN EPOXIDED CONJUGATED DIENE-VINYLAROMATIC BLOCK POLYMER DAICEL CHEMICAL INDUSTRIES LTD. (JP) 2001-01-23 US disclosed
EP-0899275-A1 BLOCK COPOLYMER HAVING (METH)ACRYLOYL GROUPS IN THE SIDE CHAINS AND COMPOSITION CONTAINING THE SAME DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 1999-03-03 EP disclosed
US-5756221-A ELECTRODEPOSITION OF CATIONIC POLYMER KANSAI PAINT CO., LTD. (JP) 1998-05-26 US disclosed
EP-0785034-A1 Coating method KANSAI PAINT CO., LTD. (JP) 1997-07-23 EP disclosed
US-5610249-A FREE RADICAL CATALYST, ORGANIC PHOSPHORUS COMPOUND KANSAI PAINT CO., LTD. (JP) 1997-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10428015-B2 Acid-resistant base and/or radical generator, and curable resin composition containing said base and/or radical generator REV1, RER1, CBR1 TSHR 1154/4885
US-10100070-B2 Borate-based base generator, and base-reactive composition comprising such base generator BLM, HPRT1, BROX TSHR 1373/4885
US-10428014-B2 Base generator, base-reactive composition containing said base generator, and base generation method HPRT1, GNG2, BLM TSHR 2081/4885
US-20190002403-A1 ACID-RESISTANT BASE AND/OR RADICAL GENERATOR, AND CURABLE RESIN COMPOSITION CONTAINING SAID BASE AND/OR RADICAL GENERATOR REV1, RER1, CBR1 TSHR 1154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.