Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643920 | 0.87 | ALDH1A1 (0.40) | ALDH1A1HPGDLMNATSHRMAPK1 | |
| SCHEMBL23009730 | 0.85 | RIPK1 (0.40) | ALDH1A1LMNANPSR1MEN1KMT2A | |
| SCHEMBL27644221 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HPGDMEN1KMT2APKM | |
| SCHEMBL27665487 | 0.82 | MEN1 (0.46) | ALDH1A1MEN1KMT2AACP3GRM2 | |
| SCHEMBL27644217 | 0.78 | PNMT (0.44) | PKMGRM2GRM3 | |
| SCHEMBL27643996 | 0.77 | GRM2 (0.46) | ALDH1A1HPGDMEN1KMT2APKM | |
| SCHEMBL27644307 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HPGDMEN1KMT2APKM | |
| SCHEMBL4988036 | 0.75 | MEN1 (0.42) | ALDH1A1HPGDLMNATSHRMAPK1 | |
| SCHEMBL27665625 | 0.74 | PNMT (0.50) | TSHRRECQLPKMGRM2GRM3 | |
| SCHEMBL10654275 | 0.74 | MEN1 (0.46) | ALDH1A1HPGDLMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |