Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 7/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041122 | 0.82 | MGLL (0.49) | PDK2HSD11B1MGLLCNR1FNTA | |
| SCHEMBL4701904 | 0.79 | HSD11B1 (0.48) | HSD11B1MAPTCNR1EP300CREBBP | |
| SCHEMBL4705022 | 0.79 | HSD11B1 (0.52) | PDK2HSD11B1MGLLCNR1EP300 | |
| SCHEMBL4703921 | 0.78 | RBP4 (0.59) | HSD11B1 | |
| SCHEMBL3025969 | 0.78 | CACNA1B (0.58) | HSD11B1MGLLCNR1CYP3A4 | |
| SCHEMBL4704307 | 0.76 | HSD11B1 (0.56) | HSD11B1MGLLCNR1FNTAFNTB | |
| Chlorobenzene SCHEMBL27720081 | 0.74 | SPR (0.45) | HSD11B1MGLLKDM4EMAPTSPR | |
| SCHEMBL12386289 | 0.73 | CYP3A4 (0.42) | PDK2SPRCYP3A4KMT2A | |
| SCHEMBL15963066 | 0.73 | OPRD1 (0.62) | KMT2A | |
| SCHEMBL4701471 | 0.73 | MEN1 (0.68) | HSD11B1MGLLMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1988908-A | Amido compounds and their use as pharmaceuticals | INCYTE SAN DIEGO INC (US) | 2007-06-27 | — | — | CN | claimed |
| CN-1988908-A | Amido compounds and their use as pharmaceuticals | INCYTE SAN DIEGO INC (US) | 2007-06-27 | — | — | CN | disclosed |