Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27876362 | 0.85 | SMN1; SMN2 (0.44) | P2RX7ALDH1A1SMN1; SMN2MAPK1NPC1 | |
| SCHEMBL8585045 | 0.82 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPK1CTSAMT-CO2 | |
| SCHEMBL25512311 | 0.81 | MMP2 (0.43) | P2RX7PTGS1PTGS2 | |
| SCHEMBL4447304 | 0.80 | ALDH1A1 (0.49) | P2RX7ALDH1A1SMN1; SMN2MAPK1MT-CO2 | |
| SCHEMBL23830227 | 0.79 | P2RX7 (0.53) | P2RX7ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL6175845 | 0.78 | MEN1 (0.49) | P2RX7ALDH1A1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL18977616 | 0.77 | ALDH1A1 (0.38) | P2RX7ALDH1A1SMN1; SMN2MAPK1CTSA | |
| SCHEMBL6017451 | 0.77 | KMT2A (0.47) | ALDH1A1MAPK1MT-CO2PTGS1PTGS2 | |
| SCHEMBL30563829 | 0.74 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPK1PTGS1PTGS2 | |
| SCHEMBL4201283 | 0.74 | MAP2K1 (0.57) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1934082-A | Organic compounds | SPEEDEL EXPERIMENTA AG (CH) | 2007-03-21 | — | — | CN | disclosed |
| CN-1910136-A | Organic compounds | SPEEDEL EXPERIMENTA AG (CH) | 2007-02-07 | — | — | CN | disclosed |