Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31042985 | 0.82 | ALDH1A1 (0.48) | ALDH1A1P2RX7HTTL3MBTL1PTGS1 | |
| SCHEMBL3741239 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK1NPC1RAB9ACYP1A2 | |
| SCHEMBL27667474 | 0.80 | P2RX7 (0.42) | ALDH1A1SMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL30563829 | 0.78 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPK1CYP1A2CYP3A4 | |
| SCHEMBL8585045 | 0.75 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPK1POLBHTT | |
| SCHEMBL13044588 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MAPTHTTNPSR1KMT2A | |
| SCHEMBL29301548 | 0.74 | NOS3 (0.39) | SMN1; SMN2MAPK1NPC1RAB9ACYP2D6 | |
| SCHEMBL827728 | 0.73 | NOS3 (0.50) | NPC1RAB9ACYP2D6MAPTFDPS | |
| SCHEMBL23747295 | 0.73 | L3MBTL1 (0.47) | SMN1; SMN2MAPK1NPC1RAB9ACYP1A2 | |
| SCHEMBL4924785 | 0.73 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118281-A1 | Amino Alcohol Derivatives And Their Use As Renin Inhibitor | NOVARTIS AG (CH) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118281-A1 | Amino Alcohol Derivatives And Their Use As Renin Inhibitor | REN, AGTR1, ADH1A | ALDH1A1 161/4885SMN1; SMN2 4687/4885MAPK1 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.