SCHEMBL2766784

SCHEMBL2766784

Cc1ccn(C(n2ccc(C)n2)(n2ccc(C)n2)[Mn](Cl)Cl)n1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.34
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NOS1 P29475 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
USP2 O75604 1/20 0.31
ALOX15 P16050 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2749111 0.73 MAPT (0.39) MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL24813878 0.70 MAPT (0.36) MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL24737152 0.70 NOS1 (0.41) MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL2766813 0.69 KMT2A (0.48) MAPTRAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL21166137 0.67 MAPT (0.34) MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL21581037 0.65 ALDH1A1 (0.33) MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL6573388 0.64
SCHEMBL21732638 0.63 RIPK2 (0.35) MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL24884220 0.63 NOS1 (0.35) MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL20830859 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266911-B1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL CO (JP) 2010-04-14 EP disclosed
US-6881802-B2 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-04-19 US disclosed
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-02-13 US disclosed
EP-1266911-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer BRAP, MCM4, BOLA2; BOLA2B MAPT 749/4885RAB9A 3554/4885NPC1 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.