Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 7/20 | 0.38 |
| ▸ | MAOB | P27338 | 7/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783304 | 0.77 | CYP2C19 (0.36) | GRM6MEN1KMT2AGRM2CYP1A2 | |
| SCHEMBL7434413 | 0.74 | MAOA (0.39) | HSD11B1MAOAMAOBKDM1AALDH1A1 | |
| SCHEMBL7444026 | 0.74 | MAOA (0.39) | HSD11B1MAOAMAOBKDM1AALDH1A1 | |
| SCHEMBL7442018 | 0.73 | MAOA (0.44) | HSD11B1MEN1KMT2AMAOAMAOB | |
| SCHEMBL7442024 | 0.73 | MAOA (0.44) | HSD11B1MEN1KMT2AMAOAMAOB | |
| SCHEMBL7444576 | 0.71 | LMNA (0.38) | HSD11B1MEN1KMT2AMAOAMAOB | |
| SCHEMBL28661279 | 0.69 | GRM6 (0.40) | HSD11B1GRM6MEN1KMT2AMAOA | |
| SCHEMBL7440895 | 0.67 | ALDH1A1 (0.36) | HSD11B1MAOAMAOBKDM1AALDH1A1 | |
| SCHEMBL7447857 | 0.67 | ALDH1A1 (0.36) | HSD11B1MAOAMAOBKDM1AALDH1A1 | |
| SCHEMBL6236002 | 0.66 | SLC6A9 (0.44) | HSD11B1HPGDUSP2ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1894206-A | N-substituted N-sulfonylaminocyclopropane compounds and pharmaceutical use thereof | JAPAN TOBACCO INC (JP) | 2007-01-10 | — | — | CN | disclosed |