Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.41 |
| ▸ | G6PD | P11413 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27726704 | 0.90 | ALOX5 (0.44) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL27380663 | 0.83 | ALOX5 (0.44) | ALOX5HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL28103270 | 0.83 | ALDH1A1 (0.34) | ALOX15GAA | |
| SCHEMBL28103547 | 0.83 | ADRB2 (0.41) | — | |
| SCHEMBL27873898 | 0.83 | NOTUM (0.36) | ALOX15GAANPC1RAB9ANOTUM | |
| SCHEMBL27873899 | 0.83 | SLC6A2 (0.38) | ALOX5 | |
| SCHEMBL27743313 | 0.82 | ALOX5 (0.48) | ALOX5ALOX12HTR3EHTR3BADRB1 | |
| SCHEMBL27873897 | 0.81 | ALOX5 (0.47) | ALOX5GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL28063442 | 0.81 | CHRNB2 (0.43) | — | |
| SCHEMBL28103276 | 0.80 | KDM4E (0.39) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892601-B | Pyridopyrazolocinnoline compound and preparation method and application thereof | 陕西大美化工科技有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-85103468-A | Prepare the method for new compound and new purposes thereof | — | 1986-09-10 | — | — | CN | disclosed |