Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27743313 | 0.84 | ALOX5 (0.48) | ALOX5MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL28103502 | 0.82 | ALOX5 (0.47) | ALOX5L3MBTL1MEN1KMT2AMGLL | |
| SCHEMBL28103270 | 0.81 | ALDH1A1 (0.34) | ATMMGLLALDH1A1GAACYP3A4 | |
| SCHEMBL27671224 | 0.81 | ALOX5 (0.41) | ALOX5L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL28835067 | 0.80 | ALOX5 (0.49) | ALOX5MEN1KMT2AMGLLNPC1 | |
| SCHEMBL28103275 | 0.79 | PRMT6 (0.37) | ALOX5 | |
| SCHEMBL27873899 | 0.78 | SLC6A2 (0.38) | ALOX5MGLL | |
| SCHEMBL28039321 | 0.75 | ADRB1 (0.45) | L3MBTL1ALDH1A1 | |
| SCHEMBL28158046 | 0.72 | FFAR4 (0.34) | ALOX5KMT2A | |
| SCHEMBL28103547 | 0.72 | ADRB2 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061950-A | Method for producing pyrazole compound | 住友化学株式会社 | 2016-10-26 | — | — | CN | disclosed |
| CN-102485743-A | Antineoplastic compound | BEIJING HANMEI PHARMACEUTICAL CO LTD | 2012-06-06 | — | — | CN | disclosed |