Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 3/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27614869 | 0.92 | AHR (0.50) | AHRKMT2AATMPDK2MKNK1 | |
| SCHEMBL3121452 | 0.76 | KMT2A (0.55) | KMT2AATMMKNK1MKNK2ALDH1A1 | |
| SCHEMBL17373230 | 0.75 | PARP1 (0.51) | AHRPDK2 | |
| SCHEMBL27370679 | 0.72 | BCAT2 (0.52) | KMT2AATMPDK2EIF4EALDH1A1 | |
| SCHEMBL3790275 | 0.72 | ALDH1A1 (0.60) | KMT2AATMALDH1A1MAPTHTT | |
| SCHEMBL2282125 | 0.72 | AHR (1.00) | AHRKMT2AMAPTHTT | |
| SCHEMBL7068918 | 0.70 | BCAT2 (0.58) | KMT2AATMPDK2MKNK1MKNK2 | |
| SCHEMBL27660734 | 0.70 | MKNK1 (0.48) | AHRMKNK1MKNK2ALPL | |
| SCHEMBL895613 | 0.69 | KMT2A (0.52) | KMT2AATMMKNK1MKNK2ALDH1A1 | |
| SCHEMBL11735266 | 0.69 | KMT2A (0.52) | KMT2AATMMKNK1MKNK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100443468-C | Process for preparing 2-halobenzamide compounds | NIHON NOHYAKU CO LTD (JP) | 2008-12-17 | — | — | CN | disclosed |
| CN-1906158-A | Process for preparing 2-halobenzamide compounds | NIHON NOHYAKU CO LTD (JP) | 2007-01-31 | — | — | CN | disclosed |