Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6286462 | 0.78 | CYP2C19 (0.53) | MAPTFKBP1AKMT2ATDP1RAB9A | |
| SCHEMBL9551409 | 0.76 | RAB9A (0.51) | MAPTFKBP1AKMT2ATDP1RAB9A | |
| SCHEMBL14139306 | 0.75 | MAPT (0.52) | MAPTKMT2ATDP1RAB9APOLB | |
| SCHEMBL5126103 | 0.75 | MAPT (0.52) | MAPTRAB9APOLBAKR1C3PHGDH | |
| SCHEMBL5126112 | 0.75 | MAPT (0.52) | MAPTRAB9APOLBAKR1C3PHGDH | |
| SCHEMBL1115881 | 0.73 | CYP1A2 (0.64) | KMT2ARAB9ANPC1POLBAKR1C3 | |
| SCHEMBL12196232 | 0.73 | MAPT (0.47) | MAPTFKBP1ARAB9APOLBAKR1C3 | |
| SCHEMBL28575185 | 0.72 | ALDH1A1 (0.68) | FKBP1AKMT2ARAB9ANPC1POLB | |
| SCHEMBL6021876 | 0.72 | KMT2A (0.43) | MAPTKMT2ATDP1RAB9ANPC1 | |
| SCHEMBL7342708 | 0.71 | MAPT (0.52) | MAPTKMT2ARAB9APOLBAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1897931-A | Inhibitors of cathepsin s | IRM LLC (BM) | 2007-01-17 | — | — | CN | disclosed |