Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370832 | 0.91 | CYP11B1 (0.52) | CYP11B1CYP11B2NPY5RKDM4ELDHA | |
| SCHEMBL7367947 | 0.80 | NPY5R (0.63) | CYP11B1CYP11B2NPY5RKDM4ELDHA | |
| SCHEMBL7370892 | 0.80 | NPY5R (0.57) | CYP11B1CYP11B2NPY5RKDM4ELDHA | |
| SCHEMBL7365631 | 0.80 | CYP11B1 (0.53) | CYP11B1CYP11B2NPY5RKDM4ELDHA | |
| SCHEMBL7369715 | 0.78 | CYP11B1 (0.52) | CYP11B1CYP11B2NPY5RKDM4ELDHA | |
| SCHEMBL7376655 | 0.78 | MGAM (0.52) | CYP11B1CYP11B2NPY5RKDM4ELDHA | |
| SCHEMBL7366314 | 0.78 | MAPK13 (0.54) | CYP11B1CYP11B2NPY5RKDM4EMAPT | |
| SCHEMBL7369697 | 0.78 | NPY5R (0.54) | CYP11B1CYP11B2NPY5RKDM4ELDHA | |
| SCHEMBL27692931 | 0.77 | NPY5R (0.47) | CYP11B1CYP11B2NPY5RKDM4EMAPT | |
| SCHEMBL7372656 | 0.76 | ALOX5 (0.50) | CYP11B1CYP11B2NPY5RKDM4ELDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |