Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675219 | 0.88 | MAOB (0.48) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL27675315 | 0.87 | MEN1 (0.44) | GRIK1MEN1KMT2AMAPTHTT | |
| SCHEMBL27693544 | 0.86 | CREBBP (0.42) | MEN1KMT2AHTTCREBBPLMNA | |
| SCHEMBL27693487 | 0.85 | LMNA (0.51) | MEN1KMT2AHTTCREBBPLMNA | |
| SCHEMBL27675110 | 0.84 | CHRM1 (0.46) | MEN1KMT2AHTTCREBBPLMNA | |
| SCHEMBL27675195 | 0.84 | CFD (0.49) | — | |
| SCHEMBL27693567 | 0.84 | CREBBP (0.47) | GRIK1CREBBPLMNA | |
| SCHEMBL27675196 | 0.83 | CREBBP (0.52) | MEN1KMT2ARAB9ACREBBPLMNA | |
| SCHEMBL27675227 | 0.83 | CFTR (0.48) | CREBBPLMNA | |
| SCHEMBL27693586 | 0.83 | MAOB (0.60) | GRIK1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006076-B | Modulators of ATP-binding cassette transporters | VERTEX PHARMA | 2010-09-29 | — | — | CN | disclosed |
| CN-101006076-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA (US) | 2007-07-25 | — | — | CN | disclosed |