Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 6/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675229 | 0.87 | KDM4E (0.45) | LMNAKDM4EALDH1A1POLBHPGD | |
| SCHEMBL27675221 | 0.86 | SERPINE1 (0.42) | CFDLMNAS1PR1S1PR3 | |
| SCHEMBL27693557 | 0.86 | LMNA (0.40) | LMNAKDM4EALDH1A1POLBHPGD | |
| SCHEMBL28766939 | 0.85 | S1PR1 (0.43) | CYP2C9LMNAS1PR1S1PR3KDM4E | |
| SCHEMBL28766933 | 0.84 | CFD (0.42) | CFDCYP2C9 | |
| SCHEMBL27675161 | 0.83 | POLB (0.43) | LMNAKDM4EALDH1A1POLBHPGD | |
| SCHEMBL27675276 | 0.81 | LMNA (0.42) | FABP4FABP5LMNAKDM4EALDH1A1 | |
| SCHEMBL27991300 | 0.81 | KDM4E (0.43) | CYP2C9LMNAKDM4EALDH1A1POLB | |
| SCHEMBL27693550 | 0.81 | NTRK1 (0.43) | CFDLMNAS1PR1S1PR3ALDH1A1 | |
| SCHEMBL27693793 | 0.80 | KMT2A (0.51) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006076-B | Modulators of ATP-binding cassette transporters | VERTEX PHARMA | 2010-09-29 | — | — | CN | disclosed |
| CN-101006076-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA (US) | 2007-07-25 | — | — | CN | disclosed |