Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | BAD | Q92934 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693793 | 0.91 | KMT2A (0.51) | KDM4ECHRM1KMT2AMEN1CASP3 | |
| SCHEMBL27693557 | 0.88 | LMNA (0.40) | KDM4ECHRM1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27675331 | 0.87 | CFD (0.41) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL27675114 | 0.86 | CHRM1 (0.39) | KDM4ECHRM1ALDH1A1KMT2AMEN1 | |
| SCHEMBL27991300 | 0.86 | KDM4E (0.43) | KDM4ECHRM1ALDH1A1MCL1BAD | |
| SCHEMBL27675161 | 0.84 | POLB (0.43) | KDM4ECHRM1ALDH1A1KMT2AMEN1 | |
| SCHEMBL27693506 | 0.83 | CREBBP (0.49) | KDM4ECHRM1ALDH1A1MCL1BAD | |
| SCHEMBL27920808 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1MCL1BADKMT2A | |
| SCHEMBL27675276 | 0.82 | LMNA (0.42) | KDM4ECHRM1ALDH1A1KMT2AHPGD | |
| SCHEMBL27693782 | 0.81 | L3MBTL1 (0.44) | KDM4ECHRM1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006076-B | Modulators of ATP-binding cassette transporters | VERTEX PHARMA | 2010-09-29 | — | — | CN | disclosed |
| CN-101006076-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA (US) | 2007-07-25 | — | — | CN | disclosed |