SCHEMBL27676004

SCHEMBL27676004

O=C(Oc1ccc(C(F)C(F)(F)C(F)(F)F)cc1)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
POLB P06746 3/20 0.37
HSD17B10 Q99714 3/20 0.36
CDC25A P30304 1/20 0.36
CDC25B P30305 1/20 0.36
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
TDP1 Q9NUW8 3/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
GRM8 O00222 1/20 0.35
GRM6 O15303 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
DRD3 P35462 1/20 0.35
GRM4 Q14833 1/20 0.35
TSHR P16473 1/20 0.35
APEX1 P27695 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4890614 0.82 POLB (0.50) ALDH1A1POLBHSD17B10MEN1KMT2A
SCHEMBL29215298 0.81 MAPT (0.51) ALDH1A1HSD17B10MEN1KMT2ATDP1
SCHEMBL2266317 0.81 ALDH1A1 (0.46) ALDH1A1POLBHSD17B10CDC25ACDC25B
SCHEMBL27676005 0.81 L3MBTL1 (0.40) ALDH1A1POLBHSD17B10CDC25ACDC25B
SCHEMBL11848517 0.81 HSD17B10 (0.52) ALDH1A1POLBHSD17B10CDC25ACDC25B
SCHEMBL873526 0.79 HSD17B10 (0.50) ALDH1A1POLBHSD17B10CDC25ACDC25B
SCHEMBL9833968 0.79 HSD17B10 (0.50) ALDH1A1POLBHSD17B10CDC25ACDC25B
SCHEMBL31541190 0.79 L3MBTL1 (0.42) ALDH1A1POLBHSD17B10CDC25ACDC25B
SCHEMBL4412401 0.79 L3MBTL1 (0.42) ALDH1A1POLBHSD17B10CDC25ACDC25B
Water SCHEMBL8588310 0.78 HSD17B10 (0.49) ALDH1A1POLBHSD17B10CDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271610-A Polyamic acid slurry for optical fiber and preparation method and application thereof 宁波博雅聚力新材料科技有限公司 2024-07-02 CN claimed
CN-118271609-A Polyamic acid slurry and preparation method and application thereof 宁波博雅聚力新材料科技有限公司 2024-07-02 CN claimed
CN-117343637-A Polyimide varnish, and preparation method and application thereof 宁波博雅聚力新材料科技有限公司 2024-01-05 CN claimed
CN-116903845-A Polyalkylene oxide end-capping agent, polyimide film with low dielectric constant, and preparation method and application thereof 宁波博雅聚力新材料科技有限公司 2023-10-20 CN claimed
CN-116903864-A Polyamic acid slurry and preparation method and application thereof 宁波博雅聚力新材料科技有限公司 2023-10-20 CN claimed
CN-116554828-A Water-soluble polyimide binder and preparation method and application thereof 宁波博雅聚力新材料科技有限公司 2023-08-08 CN claimed
CN-116444391-A Diamine monomer for preparing polyimide film, preparation method thereof and polyimide film 宁波博雅聚力新材料科技有限公司 2023-07-18 CN claimed
CN-116444394-A Diamine monomer for preparing polyimide film, preparation method thereof and polyimide film 宁波博雅聚力新材料科技有限公司 2023-07-18 CN claimed
CN-115926218-A Aromatic imide film 宁波博雅聚力新材料科技有限公司 2023-04-07 CN claimed
CN-115784923-A Diamine monomer for preparing polyimide film, preparation method of diamine monomer and polyimide film 宁波博雅聚力新材料科技有限公司 2023-03-14 CN claimed
CN-113881225-A Imide film and synthetic method thereof 宁波博雅聚力新材料科技有限公司 2022-01-04 CN claimed
CN-85101150-A The preparation method of fluorine-containing polyamide acid derivatives and polyimide 1987-01-17 CN claimed
CN-118271610-A Polyamic acid slurry for optical fiber and preparation method and application thereof 宁波博雅聚力新材料科技有限公司 2024-07-02 CN disclosed
CN-118271609-A Polyamic acid slurry and preparation method and application thereof 宁波博雅聚力新材料科技有限公司 2024-07-02 CN disclosed
CN-115044040-B Polyimide-containing polymer, positive photosensitive resin composition, negative photosensitive resin composition, and pattern forming method 信越化学工业株式会社 2024-07-02 CN disclosed
CN-115926218-B Aromatic imide film 宁波博雅聚力新材料科技有限公司 2024-06-21 CN disclosed
CN-109348718-A Polyimide resin, uses its touch panel and its manufacturing method, colour filter and its manufacturing method, liquid crystal cell and its manufacturing method, organic EL element and its manufacturing method at polyimide resin composition 东丽株式会社 2019-02-15 CN disclosed
CN-107073914-A Display supporting substrates, use its colour filter and its manufacture method, organic EL element and its manufacture method and flexible organic el display 东丽株式会社 2017-08-18 CN disclosed
CN-101265328-B Method for preparing negative photosensitive polyimide based on 2,2-di[4-(2,4-diaminophenyloxy)phenyl]hexafluoropropane UNIV DONGHUA 2010-11-17 CN disclosed
CN-101265328-A Method for preparing negative photosensitive polyimide based on 2,2-di[4-(2,4-diaminophenyloxy)phenyl]hexafluoropropane UNIV DONGHUA (CN) 2008-09-17 CN disclosed