Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27657760 | 0.95 | MAPT (0.40) | NPC1RAB9AMAPTTP53GAA | |
| SCHEMBL27963121 | 0.80 | MAPT (0.42) | NPC1RAB9AMAPTTP53MEN1 | |
| SCHEMBL27963122 | 0.78 | MME (0.42) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL28123462 | 0.77 | ALPL (0.45) | NPC1RAB9AMAPTTP53GAA | |
| SCHEMBL27657935 | 0.74 | KMT2A (0.40) | NPC1RAB9AMAPTHTTSMN1; SMN2 | |
| SCHEMBL27794706 | 0.73 | ALPL (0.37) | NPC1RAB9AMAPTGAASMN1; SMN2 | |
| SCHEMBL27963156 | 0.73 | MAPT (0.53) | NPC1RAB9AMAPTTP53GAA | |
| SCHEMBL28013858 | 0.69 | NPC1 (0.47) | NPC1RAB9AMAPTTP53GAA | |
| SCHEMBL28013861 | 0.69 | ALPL (0.40) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL27963119 | 0.69 | LMNA (0.45) | RAB9ATP53GAAMMECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1958589-A | 6 (aryloxy methyl) - 2 aryl - 6, 7 dihydro 4H - pyrido [5,1 c ] [1,4] oxaxine - 4 - ketone derivative, and preparation method | UNIV SHANDONG (CN) | 2007-05-09 | — | — | CN | disclosed |