Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MARS1 | P56192 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815832 | 0.96 | MAPT (0.37) | ALPLCA12MMEBCHEACHE | |
| SCHEMBL28788347 | 0.95 | ALPL (0.37) | ALPLCA12MMEMAPTMEN1 | |
| SCHEMBL27815972 | 0.93 | LMNA (0.38) | MMEMAPTMEN1KMT2ANPC1 | |
| SCHEMBL27963122 | 0.81 | MME (0.42) | ALPLCA12MMEMAPTMEN1 | |
| SCHEMBL27963121 | 0.78 | MAPT (0.42) | ALPLCA12MMEMAPTMEN1 | |
| SCHEMBL27657760 | 0.75 | MAPT (0.40) | ALPLCA12MMEMAPTMEN1 | |
| SCHEMBL28123462 | 0.74 | ALPL (0.45) | ALPLCA12MAPTMEN1KMT2A | |
| SCHEMBL27657935 | 0.74 | KMT2A (0.40) | ALPLCA12MMEMAPTMEN1 | |
| SCHEMBL27678048 | 0.73 | NPC1 (0.40) | ALPLCA12MMEMAPTMEN1 | |
| SCHEMBL27963119 | 0.73 | LMNA (0.45) | MMERAB9ALMNAPTPN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101870676-B | 1-(2-oximido-2-phenylethyl)-3-phenyl-1H-pyrazol-5-ethyl formate derivative as well as preparation method and application thereof | UNIV SHANDONG | 2011-09-07 | — | — | CN | disclosed |
| CN-101870676-A | 1-(2-oximido-2-phenylethyl)-3-phenyl-1H-pyrazol-5-ethyl formate derivative as well as preparation method and application thereof | UNIV SHANDONG | 2010-10-27 | — | — | CN | disclosed |