Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PSD | A5PKW4 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SLC27A2 | O14975 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27963121 | 0.91 | MAPT (0.42) | MAPTNPC1RAB9AMCL1TDP1 | |
| SCHEMBL27963148 | 0.90 | MAPT (0.39) | MAPTNPC1RAB9AMCL1TDP1 | |
| SCHEMBL27963122 | 0.85 | MME (0.42) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28030909 | 0.80 | MAPT (0.55) | MAPTNPC1RAB9AMCL1TDP1 | |
| SCHEMBL27963119 | 0.77 | LMNA (0.45) | RAB9APOLBLMNACYP2C9CYP2C19 | |
| SCHEMBL28123462 | 0.76 | ALPL (0.45) | MAPTNPC1RAB9AMCL1TDP1 | |
| SCHEMBL27963175 | 0.73 | CYP11B1 (0.38) | MAPTRAB9APOLBLMNACYP2C9 | |
| SCHEMBL27678048 | 0.73 | NPC1 (0.40) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28014533 | 0.71 | CYP2D6 (0.37) | MAPTNPC1RAB9AHTTLMNA | |
| SCHEMBL27677335 | 0.70 | MEN1 (0.40) | MAPTNPC1RAB9AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787976-A | 1-aryl-3-aryl-1H-pyrromonazole-5-hydroximic acid derivative and application thereof | UNIV SHANDONG | 2014-05-14 | — | — | CN | disclosed |