Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27963122 | 0.94 | MME (0.42) | MAPTALPLMMECA12DRD2 | |
| SCHEMBL27963156 | 0.91 | MAPT (0.53) | MAPTTP53MMENPSR1MEN1 | |
| SCHEMBL27963119 | 0.85 | LMNA (0.45) | TP53MMEDRD2DRD4DRD3 | |
| SCHEMBL28123462 | 0.84 | ALPL (0.45) | MAPTTP53ALPLCA12DRD4 | |
| SCHEMBL27963175 | 0.81 | CYP11B1 (0.38) | MAPTTP53MMEL3MBTL1RAB9A | |
| SCHEMBL28788347 | 0.80 | ALPL (0.37) | MAPTTP53ALPLMMECA12 | |
| SCHEMBL27678048 | 0.80 | NPC1 (0.40) | MAPTTP53ALPLMMECA12 | |
| SCHEMBL27963148 | 0.79 | MAPT (0.39) | MAPTMMEMEN1NPC1RAB9A | |
| SCHEMBL28014533 | 0.79 | CYP2D6 (0.37) | MAPTTP53ALPLCA12L3MBTL1 | |
| SCHEMBL28013861 | 0.76 | ALPL (0.40) | MAPTALPLCA12L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787976-A | 1-aryl-3-aryl-1H-pyrromonazole-5-hydroximic acid derivative and application thereof | UNIV SHANDONG | 2014-05-14 | — | — | CN | disclosed |