Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770304 | 0.74 | CHRM1 (0.39) | OPRK1LMNAATMSMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL27749266 | 0.73 | ATM (0.39) | SIGMAR1OPRK1LMNAATMSMN1; SMN2 | |
| SCHEMBL27679414 | 0.70 | OPRK1 (0.36) | OPRK1ATMSMN1; SMN2CHRM1OPRM1 | |
| SCHEMBL27690244 | 0.68 | OPRM1 (0.45) | OPRK1LMNATDP1CHRM1OPRM1 | |
| SCHEMBL505692 | 0.64 | TDP1 (0.40) | KCNN4SIGMAR1LMNATDP1OPRM1 | |
| SCHEMBL30681769 | 0.64 | CHRM1 (0.47) | OPRK1LMNAMAOAMAOBCHRM1 | |
| SCHEMBL5899222 | 0.63 | CHRM1 (0.46) | MAOAMAOBCHRM1OPRL1 | |
| SCHEMBL27770310 | 0.63 | OPRM1 (0.41) | OPRK1LMNACHRM1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL27749268 | 0.62 | OPRM1 (0.40) | OPRK1LMNAATMSMN1; SMN2NPSR1 | |
| SCHEMBL505691 | 0.60 | POLB (0.47) | KCNN4SIGMAR1P2RX7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1997641-A | Diarylamine derivatives as calcium channel blockers | NEUROMED PHARMACEUTICALS LTD (CA) | 2007-07-11 | — | — | CN | claimed |