Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27690244 | 0.72 | OPRM1 (0.45) | TDP1OPRM1OPRL1NR1I2RORC | |
| SCHEMBL5514318 | 0.66 | OPRM1 (0.44) | OPRM1OPRL1 | |
| Biphenyl SCHEMBL27679403 | 0.64 | KCNN4 (0.37) | TDP1OPRM1OPRL1NR1I2RORC | |
| SCHEMBL21061293 | 0.64 | OPRL1 (0.58) | OPRM1OPRL1 | |
| SCHEMBL4759637 | 0.64 | HTR2A (0.38) | OPRM1SIGMAR1POLBKMT2AALDH1A1 | |
| SCHEMBL29359141 | 0.64 | ALDH1A1 (0.40) | HTTALDH1A1LMNA | |
| SCHEMBL18088639 | 0.63 | OPRM1 (0.49) | OPRM1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL15520829 | 0.62 | MAOB (0.35) | OPRM1OPRL1MAPTALDH1A1 | |
| SCHEMBL11661570 | 0.62 | MEN1 (0.47) | OPRM1SIGMAR1MEN1KMT2AGRIN2B | |
| SCHEMBL3433975 | 0.61 | MEN1 (0.46) | OPRM1SIGMAR1MEN1KMT2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029203-A1 | Synthesis Of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2012-02-02 | — | — | US | claimed |
| US-20060041170-A1 | starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride | PHILERA NEW ZEALAND LIMITED (NZ) | 2006-02-23 | — | — | US | claimed |
| US-11795150-B2 | Synthesis of triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2023-10-24 | — | — | US | disclosed |
| US-20200148647-A1 | Synthesis of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2020-05-14 | — | — | US | disclosed |
| US-20170226064-A1 | Synthesis of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2017-08-10 | — | — | US | disclosed |
| US-9556123-B2 | Synthesis of triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2017-01-31 | — | — | US | disclosed |
| US-20160102060-A1 | Synthesis of Triethylenetetramines | PROTEMIX CORPORATION LIMITED (NZ) | 2016-04-14 | — | — | US | disclosed |
| US-20150057466-A1 | Synthesis of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2015-02-26 | — | — | US | disclosed |
| US-8912362-B2 | Synthesis of triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2014-12-16 | — | — | US | disclosed |
| US-20130345311-A1 | Synthesis Of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2013-12-26 | — | — | US | disclosed |
| EP-1778618-B1 | SYNTHESIS OF TRIETHYLENETETRAMINES | PHILERA NEW ZEALAND LTD (NZ) | 2013-12-25 | — | — | EP | disclosed |
| US-8394992-B2 | Synthesis of triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2013-03-12 | — | — | US | disclosed |
| US-20120029203-A1 | Synthesis Of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2012-02-02 | — | — | US | disclosed |
| US-8067641-B2 | Synthesis of triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2011-11-29 | — | — | US | disclosed |
| US-20100173994-A1 | Synthesis of triethylenetetramines | PROTEMIX CORPORATION LIMITED (NZ) | 2010-07-08 | — | — | US | disclosed |
| US-7582796-B2 | starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride | PROTEMIX CORPORATION LIMITED (NZ) | 2009-09-01 | — | — | US | disclosed |
| US-20060041170-A1 | starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride | PHILERA NEW ZEALAND LIMITED (NZ) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795150-B2 | Synthesis of triethylenetetramines | PNMT, TES, TPR | TDP1 1337/4885OPRM1 338/4885OPRL1 2811/4885 |
| US-20160102060-A1 | Synthesis of Triethylenetetramines | PNMT, TES, TPR | TDP1 1337/4885OPRM1 338/4885OPRL1 2811/4885 |
| US-20170226064-A1 | Synthesis of Triethylenetetramines | PNMT, TES, TPR | TDP1 1337/4885OPRM1 338/4885OPRL1 2811/4885 |
| US-20130345311-A1 | Synthesis Of Triethylenetetramines | PNMT, TES, TPR | TDP1 1337/4885OPRM1 338/4885OPRL1 2811/4885 |
| US-20120029203-A1 | Synthesis Of Triethylenetetramines | PNMT, TES, TPR | TDP1 1337/4885OPRM1 338/4885OPRL1 2811/4885 |
| US-20150057466-A1 | Synthesis of Triethylenetetramines | PNMT, TES, TPR | TDP1 1337/4885OPRM1 338/4885OPRL1 2811/4885 |
| US-20200148647-A1 | Synthesis of Triethylenetetramines | PNMT, TES, TPR | TDP1 1337/4885OPRM1 338/4885OPRL1 2811/4885 |
| US-20060041170-A1 | starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride | TET1, TET2, TET3 | TDP1 600/4885OPRM1 3118/4885OPRL1 4591/4885 |
| US-20100173994-A1 | Synthesis of triethylenetetramines | PNMT, TES, TPR | TDP1 1337/4885OPRM1 338/4885OPRL1 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.