SCHEMBL2767945

SCHEMBL2767945

C=C[Si](OC)(OC)OC.C=C[Si](Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.39
LTA4H P09960 2/20 0.34
TSHR P16473 3/20 0.32
TRPA1 O75762 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22654203 0.94 CA4 (0.41) CA4LTA4HTSHRTRPA1ALDH1A1
SCHEMBL8426084 0.94 CA4 (0.41) CA4LTA4HTSHRTRPA1ALDH1A1
SCHEMBL80762 0.89 LTA4H (0.39) CA4LTA4HTSHRALDH1A1SMN1; SMN2
Benzene SCHEMBL28104076 0.80
SCHEMBL29059249 0.79 CA4 (0.31) CA4TSHRALDH1A1
SCHEMBL1427393 0.79 LMNA (0.32) CA4
Toluene SCHEMBL28147460 0.79 ACHE (0.48) CA4TSHRALDH1A1TP53ALOX12
Styrene SCHEMBL10912513 0.78 ALDH1A1 (0.58) CA4TSHRTRPA1ALDH1A1TP53
Styrene SCHEMBL438309 0.78 ALDH1A1 (0.58) CA4TSHRTRPA1ALDH1A1TP53
SCHEMBL9496206 0.77 LTA4H (0.37) CA4LTA4HTSHRALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114126768-A Coating method 株式会社德山 2022-03-01 CN disclosed
EP-1918335-B1 Coating composition and optical articles TOKUYAMA CORP (JP) 2010-04-14 EP disclosed
EP-1568739-B1 COATING COMPOSITION AND OPTICAL ARTICLE TOKUYAMA CORP (JP) 2009-08-26 EP disclosed
US-7442734-B2 Coating composition and optical article TOKUYAMA CORPORATION (JP) 2008-10-28 US disclosed
EP-1918335-A1 Coating composition and optical articles Tokuyama Corporation (JP) 2008-05-07 EP disclosed
US-20060071203-A1 Coating composition and optical article TOKUYAMA CORPORATION (JP) 2006-04-06 US disclosed
EP-1568739-A1 COATING COMPOSITION AND OPTICAL ARTICLE Tokuyama Corporation (JP) 2005-08-31 EP disclosed