Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 4/20 | 0.39 |
| ▸ | TYK2 | P29597 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 5/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108586 | 0.78 | NPC1 (0.53) | BCAT2JAK1TYK2JAK2JAK3 | |
| SCHEMBL1644002 | 0.76 | ALDH1A1 (0.55) | BCAT2JAK1TYK2POLBCA1 | |
| SCHEMBL28816355 | 0.73 | BCAT2 (0.53) | BCAT2POLBPABPC1EIF4HCNR2 | |
| SCHEMBL2575446 | 0.73 | CA1 (0.49) | BCAT2JAK1TYK2POLBJAK2 | |
| SCHEMBL30752023 | 0.73 | CA1 (0.49) | BCAT2JAK1TYK2POLBJAK2 | |
| SCHEMBL5483549 | 0.70 | L3MBTL1 (0.50) | BCAT2POLBMAPTCNR2ADRA1A | |
| SCHEMBL2698253 | 0.70 | BCAT2 (0.50) | BCAT2TDP1PABPC1EIF4HMAPT | |
| SCHEMBL2634765 | 0.68 | HTR6 (0.62) | BCAT2JAK1TYK2POLBTDP1 | |
| SCHEMBL27698527 | 0.68 | CA1 (0.51) | BCAT2ADRA1ACA1CA2ALDH1A1 | |
| SCHEMBL7710970 | 0.68 | DHODH (0.55) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87108295-A | New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method | — | 1988-07-13 | — | — | CN | disclosed |