Water

Water

SCHEMBL27680437

FC(F)=C(F)C(F)(F)F.O

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28661060 1.00
Water SCHEMBL27507711 1.00
Water SCHEMBL31411022 1.00
SCHEMBL776976 0.96
SCHEMBL2836890 0.96
SCHEMBL18675 0.96
SCHEMBL6230404 0.92
Bromide SCHEMBL11720937 0.92
SCHEMBL5934046 0.92
Fluoride SCHEMBL547535 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111362887-B Method for preparing hexafluoropropylene oxide by catalytic oxidation 天津市长芦化工新材料有限公司 2023-06-27 CN disclosed
CN-111514923-B Modified silicon dioxide mesoporous catalyst and preparation method thereof 天津市长芦化工新材料有限公司 2023-06-27 CN disclosed
CN-111892705-A Preparation method of saturated perfluoropolyether 中国石油化工股份有限公司 2020-11-06 CN disclosed
CN-111514923-A Modified silicon dioxide mesoporous catalyst and preparation method thereof 天津市长芦化工新材料有限公司 2020-08-11 CN disclosed
CN-111362887-A Method for preparing hexafluoropropylene oxide by catalytic oxidation 天津市长芦化工新材料有限公司 2020-07-03 CN disclosed
CN-110183643-A A kind of fluorinated systems of perfluoropolyether unstable end-group 上海欧勒奋生物科技有限公司 2019-08-30 CN disclosed
CN-110121488-A Halogenated α-fluorine ethers manufacturing method 中央硝子株式会社 2019-08-13 CN disclosed
CN-110092901-A A kind of flaorination process of perfluoropolyether unstable end-group 上海欧勒奋生物科技有限公司 2019-08-06 CN disclosed
CN-109503341-A The method for preparing seven carbon ketone of perfluor five-carbon ketone and perfluor simultaneously 天津市长芦化工新材料有限公司 2019-03-22 CN disclosed
CN-105461663-B The device and method of hexafluoropropylene oxide is continuously prepared under a kind of temperate condition 天津市长芦化工新材料有限公司 2018-05-11 CN disclosed
CN-103715383-B Charge storage element 株式会社杰士汤浅国际 2017-11-03 CN disclosed
CN-106170520-A Thickening and/or dust suppression coating 3M创新有限公司 2016-11-30 CN disclosed
CN-106164187-A Adhesion promoting and/or dust suppressing coating 3M创新有限公司 2016-11-23 CN disclosed
CN-100415368-C Solid catalyst and its preparation and method of catalytic preparation epoxy propane hexafluoride DONGYUE SHENZHOU NEW MAT CO (CN) 2008-09-03 CN disclosed
CN-1954911-A Solid catalyst and its preparation and method of catalytic preparation epoxy propane hexafluoride DONGYUE SHENZHOU NEW MAT CO (CN) 2007-05-02 CN disclosed