Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680699 | 0.80 | RAB9A (0.36) | EGFRERBB2MEN1KMT2AKDM4E | |
| SCHEMBL27680696 | 0.76 | GAA (0.32) | — | |
| SCHEMBL13316538 | 0.76 | GBA1 (0.40) | KDM4EMAPK1S1PR4S1PR3 | |
| SCHEMBL27660669 | 0.75 | KDM4E (0.35) | KDM4ES1PR4S1PR3 | |
| SCHEMBL27961725 | 0.73 | ALDH1A1 (0.34) | MEN1KMT2AKDM4EATMS1PR4 | |
| SCHEMBL27680700 | 0.70 | HMOX1 (0.45) | MAPK1 | |
| SCHEMBL27680697 | 0.70 | ALDH1A1 (0.37) | — | |
| SCHEMBL27658270 | 0.68 | ALDH1A1 (0.37) | MEN1KMT2AKDM4ES1PR4S1PR3 | |
| SCHEMBL31477344 | 0.68 | ALDH1A1 (0.37) | MEN1KMT2AKDM4ES1PR4S1PR3 | |
| SCHEMBL27924986 | 0.68 | HDAC3 (0.32) | KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989134-A | 3- {4- (pyridin-3-yl) phenyl} -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents | ASTRAZENECA AB (SE) | 2007-06-27 | — | — | CN | disclosed |
| CN-1989137-A | 3- '4- {6-substituted alkanoyl) pyridin-3-yl} -3-phenyl! -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents | ASTRAZENECA AB (SE) | 2007-06-27 | — | — | CN | disclosed |