Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680694 | 0.81 | TSHR (0.39) | GAATSHRNPSR1ALDH1A1 | |
| SCHEMBL27680701 | 0.76 | EGFR (0.32) | — | |
| SCHEMBL13316538 | 0.74 | GBA1 (0.40) | ALDH1A1IDH1 | |
| SCHEMBL27680697 | 0.73 | ALDH1A1 (0.37) | TSHRALDH1A1 | |
| SCHEMBL27660669 | 0.73 | KDM4E (0.35) | TSHRALDH1A1 | |
| SCHEMBL27961725 | 0.71 | ALDH1A1 (0.34) | TSHRALDH1A1 | |
| SCHEMBL27660859 | 0.71 | FPR2 (0.32) | TSHRNPSR1ALDH1A1IDH1 | |
| SCHEMBL4893983 | 0.68 | KDM4E (0.44) | GAATSHRNPSR1ALDH1A1 | |
| SCHEMBL27680700 | 0.68 | HMOX1 (0.45) | — | |
| SCHEMBL31477344 | 0.66 | ALDH1A1 (0.37) | ALDH1A1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989137-A | 3- '4- {6-substituted alkanoyl) pyridin-3-yl} -3-phenyl! -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents | ASTRAZENECA AB (SE) | 2007-06-27 | — | — | CN | disclosed |