Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27548936 | 0.97 | LOXL2 (0.38) | LOXL2TAAR1HTR2AESR1ESR2 | |
| SCHEMBL4533823 | 0.75 | MAOA (0.40) | LOXL2TAAR1HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL272887 | 0.72 | ESR1 (0.39) | ESR1ESR2TSHRNR1H2NR1H3 | |
| SCHEMBL6841673 | 0.71 | ALDH1A1 (0.34) | ESR1ESR2TSHRNR1H2NR1H3 | |
| SCHEMBL28287944 | 0.69 | ESR1 (0.40) | ESR1ESR2SMN1; SMN2TSHRNR1H2 | |
| SCHEMBL28289364 | 0.69 | ESR1 (0.40) | ESR1ESR2TSHRNR1H2NR1H3 | |
| SCHEMBL27700114 | 0.69 | ESR1 (0.40) | ESR1ESR2TSHRNR1H2NR1H3 | |
| SCHEMBL272865 | 0.68 | ESR1 (0.37) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL5805498 | 0.67 | TDP1 (0.52) | LOXL2TAAR1HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL273159 | 0.67 | ESR1 (0.35) | TAAR1ESR1ESR2CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100506889-C | Non-balanced preparation method for double functionally-terminated polysiloxane from cyclicsiloxane anion actuated by silanol dipotassium salt | CHINESE ACAD INST CHEMISTRY (CN) | 2009-07-01 | — | — | CN | disclosed |
| CN-101007872-A | Non-balanced preparation method for double functionally-terminated polysiloxane from cyclicsiloxane anion actuated by silanol dipotassium salt | CHINESE ACAD INST CHEMISTRY (CN) | 2007-08-01 | — | — | CN | disclosed |