Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 4/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27684133 | 0.84 | FDPS (0.57) | ABCB1ENPP2RELANFE2L2APP | |
| SCHEMBL8928081 | 0.82 | RELA (0.61) | ENPP2RELANFE2L2FDPSCYP1A1 | |
| SCHEMBL8928082 | 0.82 | RELA (0.61) | ENPP2RELANFE2L2FDPSCYP1A1 | |
| SCHEMBL8904307 | 0.82 | ENPP2 (0.54) | ENPP2NFE2L2FDPSHDAC4HDAC2 | |
| SCHEMBL8904305 | 0.82 | ENPP2 (0.54) | ENPP2NFE2L2FDPSHDAC4HDAC2 | |
| SCHEMBL27698353 | 0.80 | ENPP2 (0.49) | ENPP2FDPSHDAC2HDAC8MAOB | |
| SCHEMBL27745334 | 0.79 | ENPP2 (0.40) | ENPP2FDPSNPC1RAB9AMAOB | |
| SCHEMBL442274 | 0.78 | KDM4E (0.57) | ABL1ABCB1BCRRELANFE2L2 | |
| SCHEMBL442275 | 0.78 | KDM4E (0.57) | ABL1ABCB1BCRRELANFE2L2 | |
| SCHEMBL694393 | 0.78 | ENPP2 (0.50) | ENPP2RELANFE2L2FDPSHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101053558-A | Diphenylethylene compounds and uses thereof | CELGENE CORP (US) | 2007-10-17 | — | — | CN | disclosed |