Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928082 | 1.00 | RELA (0.61) | RELANFE2L2CYP19A1NQO2TUBB4A | |
| SCHEMBL700055 | 0.82 | RELA (0.84) | RELANFE2L2CYP19A1NQO2TUBB4A | |
| SCHEMBL31317665 | 0.82 | RELA (0.84) | RELANFE2L2CYP19A1NQO2TUBB4A | |
| SCHEMBL23158820 | 0.82 | RELA (0.84) | RELANFE2L2CYP19A1NQO2TUBB4A | |
| SCHEMBL700056 | 0.82 | RELA (0.84) | RELANFE2L2CYP19A1NQO2TUBB4A | |
| SCHEMBL27684142 | 0.82 | ABL1 (0.50) | RELANFE2L2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL22029554 | 0.82 | FDPS (0.54) | RELACYP19A1NQO2TUBB4ATUBB | |
| SCHEMBL2119755 | 0.82 | RELA (0.61) | RELANFE2L2CYP19A1NQO2TUBB4A | |
| SCHEMBL2119753 | 0.82 | RELA (0.61) | RELANFE2L2CYP19A1NQO2TUBB4A | |
| SCHEMBL21457214 | 0.81 | KDM4E (0.57) | RELAENPP2ACMSDFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606824-B | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2023-03-14 | — | — | CN | claimed |
| CN-111606824-A | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2020-09-01 | — | — | CN | claimed |
| EP-4712974-A2 | STAT DEGRADERS AND USES THEREOF | Recludix Pharma, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| EP-4709370-A2 | STAT DEGRADERS AND USES THEREOF | Recludix Pharma, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024238603-A2 | STAT DEGRADERS AND USES THEREOF | RECLUDIX PHARMA, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| WO-2024233639-A2 | STAT DEGRADERS AND USES THEREOF | RECLUDIX PHARMA, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| CN-111606824-B | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2023-03-14 | — | — | CN | disclosed |
| EP-3553097-B1 | COPOLYMER AND OPTICAL FILM USING SAME | TOSOH CORP (JP) | 2022-05-04 | — | — | EP | disclosed |
| US-11225540-B2 | Copolymer and optical film using same | TOSOH CORPORATION (JP) | 2022-01-18 | — | — | US | disclosed |
| CN-110248971-B | Copolymer and optical film using the same | 东曹株式会社 | 2021-11-02 | — | — | CN | disclosed |
| CN-111606824-A | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2020-09-01 | — | — | CN | disclosed |
| US-20150087633-A1 | SYNTHESIS OF POLYCYCLIC ALKALOIDS | RIGEL PHARMACEUTICALS, INC. (US) | 2015-03-26 | — | — | US | disclosed |
| EP-2828263-A1 | SYNTHESIS OF POLYCYCLIC ALKALOIDS AND THEIR USE AS TGR5 AGONISTS | Rigel Pharmaceuticals, Inc. (US) | 2015-01-28 | — | — | EP | disclosed |
| US-8927564-B2 | Synthesis of polycyclic alkaloids | RIGEL PHARMACEUTICALS, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20130237524-A1 | SYNTHESIS OF POLYCYCLIC ALKALOIDS | RIGEL PHARMACEUTICALS, INC. (US) | 2013-09-12 | — | — | US | disclosed |
| WO-2013134527-A1 | SYNTHESIS OF POLYCYCLIC ALKALOIDS AND THEIR USE AS TGR5 AGONISTS | RIGEL PHARMACEUTICALS, INC. (US) | 2013-09-12 | — | — | WO | disclosed |
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087633-A1 | SYNTHESIS OF POLYCYCLIC ALKALOIDS | PNMT, ACHE, PRMT5 | RELA 771/4885NFE2L2 2387/4885CYP19A1 416/4885 |
| US-20130237524-A1 | SYNTHESIS OF POLYCYCLIC ALKALOIDS | PNMT, ACHE, PRMT5 | RELA 771/4885NFE2L2 2387/4885CYP19A1 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.