Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28761478 | 0.89 | RAB9A (0.51) | PTGDR2RAB9ANPC1MAPTHPGDS | |
| SCHEMBL28765396 | 0.86 | RAB9A (0.49) | PTGDR2RAB9ANPC1MAPTHPGDS | |
| SCHEMBL27665937 | 0.86 | PTGDR2 (0.52) | PTGDR2RAB9ANPC1MAPTHPGDS | |
| SCHEMBL6157002 | 0.77 | MAPT (0.62) | PTGDR2RAB9ANPC1ARMAPT | |
| SCHEMBL15516165 | 0.76 | MAPT (0.59) | RAB9ANPC1MAPTCRHBPCRHR2 | |
| SCHEMBL8949976 | 0.74 | MAPT (0.54) | RAB9ANPC1MAPTCRHBPCRHR2 | |
| SCHEMBL27684819 | 0.73 | HPGDS (0.51) | PTGDR2RAB9ANPC1MAPTHPGDS | |
| SCHEMBL9306479 | 0.73 | KMT2A (0.54) | RAB9ANPC1MAPTCRHBPCRHR2 | |
| SCHEMBL27665788 | 0.73 | HPGDS (0.51) | PTGDR2RAB9ANPC1MAPTHPGDS | |
| SCHEMBL27685236 | 0.73 | LDHA (0.51) | PTGDR2AURKARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980664-B | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS | 2011-02-23 | — | — | CN | disclosed |
| CN-1980664-A | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS (DK) | 2007-06-13 | — | — | CN | disclosed |