Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704470 | 0.79 | PRKCZ (0.37) | PRKCZPKMGAAMAPTHPGD | |
| SCHEMBL27640347 | 0.70 | MGLL (0.40) | PRKCZGAAALOX5ALDH1A1KDM4E | |
| SCHEMBL27640360 | 0.70 | HTR3E (0.37) | PRKCZGAAMAPTALOX5ALDH1A1 | |
| SCHEMBL8230851 | 0.69 | MAPT (0.43) | PKMGAAMAPTHPGDRECQL | |
| SCHEMBL28523211 | 0.65 | KMT2A (0.47) | PRKCZGAAMAPTALDH1A1KDM4E | |
| SCHEMBL27750483 | 0.64 | LOX (0.36) | GAAMAPTHPGDALDH1A1KDM4E | |
| SCHEMBL28430900 | 0.63 | PRKCZ (0.42) | PRKCZGAAMAPTKDM4EKMT2A | |
| SCHEMBL11057701 | 0.60 | ABL1 (0.48) | PRKCZGAAMAPTALOX5KDM4E | |
| SCHEMBL5929007 | 0.59 | MAPT (0.50) | PKMGAAMAPTALDH1A1KDM4E | |
| SCHEMBL5485154 | 0.59 | L3MBTL1 (0.51) | PKMGAAMAPTHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101018779-A | Triazole compounds and their use as metabotropic glutamate receptor antagonists | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | CN | disclosed |